Images are provided by Shutterstock & our contributors. Low estrogen is typically seen in younger women and women approaching menopause. Last medically reviewed on July 22, 2020. DIM can mitigate the level of estrogen in the body by stimulating the breakdown of estrogen in beneficial metabolites. Anti-cancer Properties: Diindolylmethane can prevent and stop certain cancers from developing by controlling estrogen levels. DIM is a compound your body makes from cruciferous vegetables. Benefits of DIM Supplement. Estrogen Metabolism Benefits of DIM Plus Estrogen metabolism can have a positive effect on acne and other skin issues. Some of the benefits being researched include a positive impact on cancerous cell growth, reduction in acne, prevention of an enlarged prostate, and treatment of the premenstrual syndrome. Read on to learn more about the benefits of supplementing with DIM, as well as the specific effects of using DIM Plus. But there’s no proof DIM actually works for endurance or sexual performance. Photo Credit: Shutterstock. Still, it’s important to remember that research is lacking on all of these effects. Some of the benefits being researched include a positive impact on cancerous cell growth, reduction in acne, prevention of an enlarged prostate, … Cut rosemary on the new growth. A DIM supplement is a nutritional supplement composed of a phytochemical that our body naturally produces by breaking down a compound in our diet. Rash, nausea, vomiting, headache, arthralgia and hot flashes have been reported. © 2005-2020 Healthline Media a Red Ventures Company. The study divided the women into two groups; the first group was to take a 150g DIM supplement twice daily, and the second group was to take a placebo. However, in a 6-month study in 551 women with cervical abnormalities, taking 150 mg of DIM per day had no effect on cervical cell changes (3, 13). While testosterone is known as a male hormone, it is also produced in a woman’s body, but instead, it converts into estrogen. In supplement form, DIM is frequently prescribed for survivors of breast, uterine and colorectal cancer. People on hormone therapies or with certain hormone-related cancers should avoid these supplements. Taking DIM can help with menopause symptoms like weight gain, hot flashes, mood swings, etc. Benefits of DIM Supplements. The entire list of reference links is also provided at the bottom of the article. Due to limited research, proper dosages for DIM are unknown. Although research is ongoing, increasing the ratio of 2-hydrozyestrone to 16-hydrozyesterone may reduce breast cancer risk and cause anti-tumor effects (8). Benefits of DIM There are a number of positive effects of DIM in the body, but there has been a decided lack of research on this substance or its potential impact on long-term health. Trying to choose a supplement to combat your PMS or PMDD? Thus, you should talk to your healthcare provider before taking DIM supplements. Before adding a DIM supplement to your diet, be sure to speak with your doctor about any risks or potential interactions. To increase transparency to the user, we provide reference links marked by numbers in parentheses in the copy of the article. Diindoylmethane (DIM) is a molecule which is named after its structure, two indole groups attached to a methane group. John Staughton is a traveling writer, editor, publisher and photographer with English and Integrative Biology degrees from the University of Illinois in Champaign-Urbana (USA). Uses and potential benefits of DIM supplements, Cruciferous Vegetables: Health Benefits and Recipes. DIM supplements may: Suppress tumor growth; Aid fat loss; Reduce hormonal acne; Balance estrogen levels; Protect against some cancerous tumors; Prevent or treat thyroid disorders How to Use DIM for Hormonal Acne. Your body produces diindolylmethane, or DIM, from substances naturally found in cruciferous vegetables. Diindolylmethane, or DIM, is a natural chemical formed in your digestive tract from a compound called glucobrassicin, which is contained in cruciferous vegetables such as broccoli, cauliflower and cabbage. This article reviews 12 actions you can take to help your hormones function optimally. DIM supplements contain diindolymethane, which is found in cruciferous vegetables like broccoli and cabbage. Different DIM products will also have different concentrations and compositions, so always read the label and directions carefully. These compounds compete with iodine for binding in the thyroid, potentially contributing to hypothyroidism. Current human research doesn’t show DIM supplements to be toxic or have serious side effects. Vitamonk Nutri DIM Supplement still provides ample benefits like helping with menopause symptoms and balancing hormone levels like most others on the list. Specifically, DIM may stimulate the production of a less potent, more beneficial form of estrogen known as 2-hydroxyestrone (1). DIM is derived from cruciferous vegetables like Broccoli. You can continue to get DIM through eating cruciferous vegetables and letting your body do the natural process to produce DIM; but be careful how you cook these vegetables. Adding DIM supplements to your diet can help to strengthen the reactivity and response time of your immune system, among others, despite the relative dearth of conclusive research on the subject. DIM is found in cruciferous vegetables such as broccoli, Brussels sprouts, cabbage, and kale. Keep in mind that human studies are needed. Given that estrogen plays an important role in regulating fat accumulation, DIM supplements may aid weight loss — although no human research currently supports this effect. Average rating 5.0 out of 5.0 based on 2 user(s). The appropriate amount for each individual will depend on a number of factors, including age, weight, prior medical conditions, and current medications. Other uses of DIM supplements, such as weight loss and acne treatment, have not been studied in humans. If you’re looking for a quality DIM supplement, DrFormulas® DIM Plus BioPerine for Men & Womenprovides a convenient once-daily dose of all the DIM you need. Every now and then, I like to highlight a particular supplement that my audience may not be aware of, and go in-depth about its uses, benefits, and potential drawbacks. Test-tube and animal studies likewise suggest that DIM helps fight prostate cancer. While the exact mechanism is unknown, indole-3-carbinol is thought to be partly responsible (4, 5, 6). DIM supplements are attracting a lot of attention recently as they have been touted to have properties that could minimize the risk of cancer. You can use Diindolylmethane (DIM) supplements for several health benefits that you can also avail from vegetables like Broccoli. Diindolylmethane, more commonly abbreviated to DIM, is a beneficial supplement that can help our body regulate itself more efficiently. The byproduct of this estrogen breakdown process is linked to lower inflammation levels and can control other symptoms related to prostatitis, such as incontinence and other issues related to urination. Although DIM is not suitable for everyone, DIM appears to have benefits for both men and women, and DIM side effects are minimal. Still, more human research is necessary (15). Healthline Media does not provide medical advice, diagnosis, or treatment. Intriguingly, observational studies associate high cruciferous vegetable intake with a reduced risk of certain cancers, including breast and prostate cancer. All the same, human studies are needed (10, 11, 12). While cruciferous vegetables are the primary food source of DIM, you would need to eat several servings every day to reap this compound’s benefits (1). Cruciferous vegetables are low-calorie, and rich in folate, vitamins C, E, and K, and fiber. But this does not mean that DIM is always safe in supplemental form. It is used as a food supplement, mainly for women in forties to keep away from breast cancer. If you take a DIM supplement, you’re bypassing these steps but can still take full advantage of the health benefits of DIM. However, a study in 24 healthy people found that although DIM doses of up to 200 mg were well tolerated and didn’t cause side effects, one person experienced nausea, headache, and vomiting after taking a 300-mg dose, suggesting that higher doses may be associated with adverse side effects (15). Some people use DIM supplements to help them lose weight, and … Word is getting out, and DIM has started picking up steam as a supplement of choice to deal with a variety of issues such as acne, PMS, mood swings, fibroids, menopause symptoms, and even things like man boobs. How to Use DIM. While it’s predominately lauded for its hormone support benefits, DIM has been picking up steam for its metabolic benefits too. Test-tube and animal studies indicate that DIM protects against ovarian, prostate, and colon cancers as well. last updated - February 05, 2020 There are a number of positive effects of DIM in the body, but there has been a decided lack of research on this substance or its potential impact on long-term health. As it affects estrogen levels, DIM may help treat a variety of conditions, including hormone-sensitive cancers and prostate issues. The fact that DIM can stimulate the breakdown of estrogen into healthy byproducts means that it is a promising complementary treatment to cancer, but more research is required, beyond the work of Dr. Thomson, Ho, and Strom in Nutrition Reviews. How to get oil out of clothes? Read on to find out about the health benefits of DIM for your whole family. A 30-day study in 19 post-menopausal women with early-stage breast cancer found that taking 108 mg of DIM per day also resulted in beneficial changes in estrogen levels (9). DIM helps in weight loss – Most women struggling with seemingly impossible weight loss is due to imbalanced estrogen. As DIM supplements interact with estrogen levels, they may affect people with hormone-sensitive cancers or who are on hormone therapies. After all, vegetables like broccoli and kale are rich sources of important nutrients, including fiber, antioxidants, vitamins, and minerals. by John Staughton (BASc, BFA) An average diet will likely contain less than 25 mg of diindolylmethane per day, yet some supplements may offer more than 500mg in a daily dose. DIM has been the topic of recent discussions surrounding hormonal health and your menstrual cycle. These amounts can increase three to four times on an individual basis to derive needed benefits for hormone balance and metabolism. Furthermore, DIM supplements may stimulate fat breakdown and inhibit fat cell formation. DIM supplements resulted in a significantly improved ratio of two types of estrogen — 2-hydroxyestrone and 16-hydrozyestrone (8). It can also be a helpful tool for those struggling to reduce body fat in specific areas of the body. Hormonal acne occurs when there is an unbalance of estrogen levels and an increase in the male hormone, testosterone. He co-founded the literary journal, Sheriff Nottingham, and now serves as the Content Director for Stain’d Arts, a non-profit based in Denver, Colorado. It’s also concentrated and sold as a supplement. Such individuals should steer clear of DIM supplements unless under the supervision of a medical professional. Therefore, a recommended dose from a supplement would look more like 100 to … Now a newâ¦, COVID-19 shows a wide range of manifestations among those affected. DIM has been intensely studied for its beneficial biochemical effects inside your body. Some of the benefits being researched include a positive impact on cancerous cell growth, reduction in acne, prevention of an enlarged prostate, and treatment of the premenstrual syndrome. BENEFITS FOR MEN – LEAN MUSCLE MASS BUILDING & MORE* DIM acts as an Estrogen Blocker inhibits the Aromatase enzyme that converts testosterone into estrogen and helps prevent estrogen dominance, providing natural testosterone support. Learn how to identify the symptoms, what causes it, and more. Due to insufficient evidence, dosage information for DIM is lacking. DIM, short for diindolylmethane, is a hormone balancer. This supplement helps to free up the bound testosterone, promote lean muscle mass building, support weight management, enhance athletic … Negative interactions with diuretic medications and liver medications have also been reported, as DIM may speed up how quickly medications are broken down in the liver. There have been rare instances when certain rice noodle brands may contain gluten. The antioxidant and anti-inflammatory properties of turmeric, mainly due to its compound curcumin, is responsible for weight loss. not the BioResponse version) is not absorbed very well (or at least this is claimed by BioResponse). While estrogen is the hormone typically associated with females, it is also present in males, and the balance of testosterone and estrogen in the body can have noticeable side effects when out of balance. DIM exerts an anti-fibrosis, anti-tumor, antioxidant, immunomodulatory, detoxification and anti-inflammation effects on liver protection. This week, I'd like to talk to you about DIM. DIM is thought not to have goitrogenic properties. Our DIM hormone therapy supplement is derived from broccoli and pomegranate. We source information from studies, clinical trial findings, and meta-analyses published in peer-reviewed journals. Therefore, it’s best to talk to your healthcare provider to obtain personalized dosage recommendations based on your intended use. This juice also helps in soothing acidity. On average 10-20 percent of I3C is metabolized to DIM. Some websites say DIM can even help with sexual function in both men and women. Debra Sullivan, Ph.D., MSN, R.N., CNE, COI, PMS Supplements: 7 Options for Mood Swings and Other Symptoms, Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, 7 Foods for Lowering Estrogen Levels in Men, Natural and Pharmaceutical Estrogen Blockers for Men, 12 Natural Ways to Boost Estrogen in Your Body, Our Favorite Healthy Finds: Organic Beauty Products for Acne-Prone Skin. In addition to Diindolylmethane, they also have a chemical called indole-3-carbinol. Diindolylmethane is used for preventing breast, uterine, and colorectal cancer. Benefits are a lot, a few proved with research and others are still being studied. Here's what you need to know about how they work and if … What Are the Symptoms of Low Estrogen in Women and How Are They Treated? We are still learning more about the powerful effects of this plant-based nutrient, but here are a few of the science-backed benefits. Nonetheless, further studies are needed — particularly for uses related to acne, weight loss, and PMS symptoms, which aren’t currently backed by human research. A yearlong study gave 130 women with breast cancer on tamoxifen therapy either a placebo or 150 mg of DIM twice a day. DIM ameliorates experimental liver fibrosis induced by thioacetamide in mice [ 35 ]. ✓ Evidence Based. As stated in Clinical Naturopathy: In Practice, by regulating the levels of both testosterone and estrogen, it can help to reduce hormonal breakouts of acne, particularly those that occur around the time of menstruation in so many women, a condition known as cystic acne. Many of the published studies on the benefits of DIM have used BioResponse DIM because generic DIM (ie. Read more! As a result, DIM supplements have been gaining popularity as a potential treatment for a variety of hormone-related conditions, including acne, menopause symptoms, prostate issues, and certain forms of cancer. Estrogen dominance can play a role in the development of acne because it can lead to oily skin and clogged pores. Take DIM with Milk Thistle for Liver detox & Endometriosis: Taking DIM with another supplement called milk thistle has been shown to reduce the severity of endometriosis. DIM supplements are being studied for their protective effects against certain cancers. Although research on DIM is still quite limited, it’s thought to help balance estrogen levels in your body (1). However, it is not a plant estrogen or an estrogen mimic, like soy isoflavones. As a supplement, Diindolylmethane comes with many benefits for the human body. Again, due to the effect that DIM can have on estrogen, including its breakdown into more beneficial metabolites, some men use this supplement to manage their prostate size. Before taking these supplements, get dosage guidance from your healthcare provider. To get maximum benefit from DIM look for it as a supplement. 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